Video

Terri E. Weaver, PhD, RN, on Efficacy of Solriamfetol for Treating Symptoms of Obstructive Sleep Apnea

01/14/2021

In this video, Terri E. Weaver, PhD, RN, talks about the effectiveness of solriamfetol in improving daily functioning, reducing daytime sleepiness, and enhancing work productivity.

Additional Resource:

Terri E. Weaver, PhD, RN, is dean and professor in the Department of Behavioral Nursing Science in the College of Nursing and professor in the Division of Pulmonary, Critical Care, Sleep, and Allergy in the Department of Medicine in the College of Medicine at the University of Illinois at Chicago.

TRANSCRIPT:

My name is Terri Weaver, I am Dean and professor at the University of Illinois Chicago College of Nursing.

This was a study to look at the effectiveness as opposed to the efficacy of solriamfetol with particular outcomes of daily functioning, daytime sleepiness, and also work productivity, along with perception of change by the patient and also the clinician.

It is approved for daytime sleepiness and patients with obstructive sleep apnea. It’s also approved for the treatment of sleepiness and narcolepsy. It is approved for 3 doses—75 mg, 150 mg, and 300 mg.

The findings showed that when this was evaluated, especially with a withdrawal phase that included a placebo, that the efficacy of solriamfetol was maintained long term, 40 weeks out.

So, the initial studies with clinical trial that was done to prove efficacy of solriamfetol showed that it was efficacious for daytime sleepiness, daily functioning, and work productivity. This study showed that efficacy was maintained long term, which was clinical effectiveness. And so, it has both efficacy and effectiveness

A component of the study was a withdrawal phase where individuals who were on doses that treated their sleepiness, when you withdrew that, in fact, they were still able to see the benefit in several outcomes that were the case with regard to the initial evaluation of the agent and that those who were placed on placebo during that time had a decline.

Thank you for the opportunity to share our work, greatly appreciate it.

Related Content

Rheumatology
Rheumatology
How to Communicate Empathetically With Your Patients
12/17/2020
In this video—with the help of a simple mnemonic device using the word "EMPATHY"—Leonard Calabrese, DO, discusses how you can increase and refine the empathetic communication skills you use with patients in...
12/17/2020
Cardiovascular Diseases
Christie Ballantyne
Cardiovascular Diseases
Christie Ballantyne, MD, on Strategies for Ensuring Patients Adhere to Statins
09/05/2018
In this video, Christie Ballantyne, MD, who is Chief of Cardiology and Cardiovascular Research at Baylor College of Medicine in Houston, Texas, talks about strategies for ensuring patients adhere...
09/05/2018
Primary Care
Deb Brown
Primary Care
Deb Drown on Let's Talk Lung Cancer
04/12/2018
Deb Brown from the American Lung Association talks to us about lung cancer and the LUNG FORCE initiative at the LUNG FORCE Expo on March 27, 2018.
04/12/2018
Gastroenterology
video
Gastroenterology
Key Insights: New Directions in Ulcerative Collitis
08/07/2018
08/07/2018
Inflammatory Bowel Disease
Lauren George, MD
Inflammatory Bowel Disease
Lauren George, MD, Previews Talk on Complicated Crohn Disease
09/10/2020
In this 2-minute video, Lauren George, MD, from the University of Maryland School of Medicine, previews her talk on managing complicated Crohn disease, which she will present on September 12 at the virtual...
09/10/2020