Chronic Lymphocytic Leukemia

Disease State Hub

Research Summaries

Leukemia

CAR-T Cell Therapy Highly Effective in Some Patients with Leukemia

07/20/2017

In a recent study, researchers evaluated the safety and efficacy of a certain chimeric antigen receptor–modified T cell therapy in patients with chronic lymphocytic leukemia. To see results of the study,...

07/20/2017

Research Summaries

Research Summary

Study: Venetoclax-Obinutuzumab Improves Progression-Free Survival in Untreated Chronic Lymphocytic Leukemia

01/14/2025

Miranda Manier, BA

A recent phase 3 study found that venetoclax-obinutuzumab improves progression-free survival and quality of life compared with chlorambucil-obinutuzumab in patients with untreated chronic lymphocytic...

01/14/2025

Research Summary

Does Ibrutinib-Venetoclax Therapy Improve Outcomes in Untreated Chronic Lymphocytic Leukemia Compared With Fludarabine-Cyclophosphamide-Rituximab?

01/07/2025

Miranda Manier, BA

A recent phase 3 trial demonstrated that a personalized approach using ibrutinib-venetoclax therapy, based on measurable residual disease, improves progression-free survival and overall survival in patients...

01/07/2025

FDA Alert

FDA Grants Accelerated Approval for First CAR-T Cell Treatment for Relapsed or Refractory Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma

04/22/2024

Anthony Calabro, MA

The FDA previously approved lisocabtagene maraleucel as a second-line treatment option for adult patients with large B-cell lymphoma in June 2022.

04/22/2024

research summary

research summary

Risk of Infections Among Patients With AML, CLL Treated With Venetoclax

03/26/2024

Leigh Precopio

Researchers examined if venetoclax—a therapy commonly used in the treatment of acute myelogenous leukemia and chronic lymphocytic leukemia—was associated with an increased risk of opportunistic infections,...

03/26/2024

Conference Coverage

Study Finds Slightly Lower Risk of Richter Transformation for Patients With Chronic Lymphocytic Leukemia in the “Novel Agent Era”

03/13/2024

Anthony Calabro, MA

The study findings potentially challenge the conventional wisdom that the risk of Richter transformation would increase as patients with chronic lymphocytic leukemia live longer with novel treatments. This...

03/13/2024

January 2025

Current Issue

January 2025

Volume 65

Issue 1