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WHO Updates Guidelines for Improved Access to HIV Post-Exposure Prophylaxis

03/25/2025

Anthony Calabro, MA

In July 2024, WHO updated its guidelines with new recommendations to improve access to HIV post-exposure prophylaxis (PEP), which involves the administration of antiretroviral medications to individuals at...

03/25/2025

Pop Quiz

Pop Quiz

New HIV Infections by Age Group

03/12/2025

Anthony Calabro, MA

In 2022, there were an estimated 31,800 new HIV infections in the United States. Do you know which age group accounted for the largest number of new infections? Take the quiz to test your knowledge!

03/12/2025

Conference Coverage

Conference Coverage

Sexual Health & Wellness in Primary Care

09/19/2024

Ryan Holley-Mallo, PhD, DNP, NP-C

Ryan Holley-Mallo, PhD, DNP, NP-C ...

Ryan Holley-Mallo, PhD, DNP, NP-C discusses the ways to approach sensitive conversations pertaining to sexual health in his PUPC 2024 session, “Sexual Health & Wellness in Primary Care." In his session, he...

09/19/2024

Interactive Features

Pop Quiz

WHO Updates Guidelines for Improved Access to HIV Post-Exposure Prophylaxis

03/25/2025

Anthony Calabro, MA

03/25/2025

Pop Quiz

New HIV Infections by Age Group

03/12/2025

Anthony Calabro, MA

In 2022, there were an estimated 31,800 new HIV infections in the United States. Do you know which age group accounted for the largest number of new infections? Take the quiz to test your knowledge!

03/12/2025

pop quiz

Common Barriers to PrEP Uptake

06/25/2024

A survey examined common barriers to pre-exposure prophylaxis uptake among men who have sex with men. Take this pop quiz to test your knowledge!

06/25/2024

Poll

Prescribing PrEP in Primary Care

05/08/2024

As a primary care practitioner, do you prescribe pre-exposure prophylaxis (PrEP) to eligible patients who are at risk of acquiring HIV infection?

05/08/2024

Pop Quiz

HIV Infection in Patients Using PrEP

11/27/2023

Which of the following are characteristics of primary HIV infection in users of pre-exposure prophylaxis?

11/27/2023

Clinical Insights

Conference Coverage

Sexual Health & Wellness in Primary Care

09/19/2024

Ryan Holley-Mallo, PhD, DNP, NP-C

Ryan Holley-Mallo, PhD, DNP, NP-C ...

09/19/2024

podcast

podcast

Pharmacy Integration in HIV Prevention Services

09/14/2024

Natalie D. Crawford, PhD

In this podcast, Natalie D. Crawford, PhD, discusses the results of her team's recent study examining the potential benefits of pharmacy integration in increasing access and use of preexposure prophylaxis...

09/14/2024

expert Q&A

Achieving Perinatal HIV Elimination Goals

08/12/2024

Margaret A. Lampe, RN, MPH

In this expert Q&A, Margaret A. Lampe, RN, MsC, discusses the elimination of perinatal HIV transmission, elimination goals set out by the CDC, next steps for research, and more.

08/12/2024

expert Q&A

Hepatitis B Virus Screening and Vaccination in Patients Prescribed PrEP

05/02/2024

Melissa E. Badowski, PharmD, MPH

In this expert interview, Melissa E. Badowski, PharmD, MPH, provides an overview of her presentation at IDWeek 2023 titled, "Guideline Adherence to Hepatitis B Virus Screening and Vaccination in Patients...

05/02/2024

Multidisciplinary Roundtable

Multidisciplinary Roundtable

The Multidisciplinary Approach in HIV Prevention, PrEP Uptake

04/04/2024

Jeffrey Kwong, DNP, MPH, ANP-BC

In this roundtable discussion, Jeffrey Kwong, DNP, MPH, ANP-BC, interviews John J. Faragon, PharmD, BCPS, BCGP, AAHIVP, Damon Jacobs, Rasheeta Chandler, MD, Jonathan Appelbaum, MD, and Princy N. Kumar, MD,...

04/04/2024

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Pre-exposure prophylaxis (PrEP) is a preventive medication administered intravenously or orally to reduce the risk of human immunodeficiency virus (HIV) infection that may occur following sex or injection drug use.

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Any licensed health care provider can prescribe PrEP. Among clinicians who are most likely to prescribe PrEP are:

primary care providers; internal medicine specialists; infectious disease specialists

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Individuals at risk of HIV transmission include:

People who have had anal or vaginal sex in the past 6 months and:
- had a partner with HIV

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Individuals at risk of HIV transmission include:

People who have had anal or vaginal sex in the past 6 months and:
- had sex without consistently using a condom

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Individuals at risk of HIV transmission include:

People who have had anal or vaginal sex in the past 6 months and:
- have been diagnosed with a sexually transmitted disease in the past 6 months

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Individuals who are at risk of HIV transmission include:

Individuals who inject drugs, have an injection partner with HIV, or share needles, syringes, or other drug injection equipment

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Individuals who are at risk of HIV transmission include:

Individuals who have previously been prescribed PrEP, have reported continued risky behavior, or previously used multiple courses of PrEP

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The HIV Risk Incidence Index for Men Who Have Sex With Men (HIRI-MSM) and Injection Drug Users Risk Index (IDU) are often used to stratify risk in patients.

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PrEP may reduce HIV transmission from sex by 99% when taken as prescribed.

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The use of PrEP among recommended users increased from 3% in 2015 to 25% in 2020.

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Sources:

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HIV Prevention Snapshot

Reviewed by Daniel Erias, MD and Jeffrey Kwong, DNP, MPH, AGPCNP-BC

Research Summaries

research summary

research summary

Directly Observed Therapy Accurately Measures PrEP Adherence

09/26/2023

Leigh Precopio

Pre-exposure prophylaxis (PrEP) adherence continues to be one of the main challenges for the elimination of HIV transmission. Researchers tested the use of an automated directly observed therapy...

09/26/2023

research summary

research summary

Text Message Intervention Supports PrEP Adherence Among Some At-Risk Populations

08/28/2023

Leigh Precopio

In a recent study, researchers examined the effectiveness of text messaging to support the use of pre-exposure prophylaxis use in certain patient populations who are at high-risk of HIV infection.

08/28/2023

research summary

Individuals Seeking Mpox Vaccination Are Also at Increased Risk of STIs, HIV

04/27/2023

Leigh Precopio

Researchers aimed to determine the risk profile of individuals without HIV who were seeking vaccination against mpox and if these patients would benefit from HIV pre-exposure prophylaxis use.

04/27/2023

CONFERENCE CONVERAGE

Urine Test Shows Predictive Values for PrEP Adherence

04/24/2023

Researchers determined the predictive value of urine point-of-care tenofovir antibody test and compared the results against self-reported PrEP use and TFV-diphosphate levels in dried blood spots. Their...

04/24/2023

Conference Coverage

TDF/FTC Considered Safe Among Pregnant Women Per Objective TFV-DP Levels

03/20/2023

Researchers compared pre-exposure prophylaxis (PrEP) use with birth outcomes using objective levels of tenofovir-diphosphate (TFV-DP) in dried blood spots (DBS) of women during the second or third trimester...

03/20/2023

March 2025

Current Issue

March 2025

Volume 65

Issue 3